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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BLM
All Species:
15.76
Human Site:
S518
Identified Species:
26.67
UniProt:
P54132
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54132
NP_000048.1
1417
159000
S518
L
G
K
K
N
E
S
S
Y
F
P
G
N
V
L
Chimpanzee
Pan troglodytes
XP_510594
1417
158822
S518
L
G
K
K
N
E
S
S
Y
F
P
G
N
V
L
Rhesus Macaque
Macaca mulatta
XP_001097543
1416
158885
S517
L
G
K
K
N
E
S
S
Y
F
P
G
N
V
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88700
1416
158347
T523
M
E
N
R
N
E
S
T
D
F
P
G
S
V
L
Rat
Rattus norvegicus
Q6AYJ1
621
69624
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515695
791
89186
Chicken
Gallus gallus
Q9I920
1142
126164
D299
H
F
D
I
D
D
L
D
E
G
W
E
E
A
V
Frog
Xenopus laevis
Q9DEY9
1364
152305
P488
S
N
S
R
F
N
T
P
Q
N
E
K
P
I
S
Zebra Danio
Brachydanio rerio
XP_701357
1261
139417
S418
G
S
S
R
T
S
H
S
D
S
V
S
T
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
D596
S
G
M
D
D
D
E
D
D
L
E
G
L
L
A
Honey Bee
Apis mellifera
XP_396209
961
109321
S118
I
I
I
S
D
S
D
S
N
S
P
S
F
K
H
Nematode Worm
Caenorhab. elegans
O18017
988
110641
V145
D
S
F
D
N
F
H
V
G
S
T
S
E
E
V
Sea Urchin
Strong. purpuratus
XP_001175892
1394
152920
S522
P
S
G
L
S
T
A
S
S
T
M
S
S
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35187
1447
163819
P539
S
F
G
R
Q
H
M
P
M
S
H
S
D
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.1
N.A.
N.A.
76.9
21.2
N.A.
46.3
47.9
50.8
41.6
N.A.
27.8
30.9
26.5
31.5
Protein Similarity:
100
99.2
97.7
N.A.
N.A.
85.2
30.9
N.A.
50.1
60.7
66.6
54
N.A.
47
47.1
40.2
47.6
P-Site Identity:
100
100
100
N.A.
N.A.
53.3
0
N.A.
0
0
0
6.6
N.A.
13.3
13.3
6.6
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
80
0
N.A.
0
20
20
13.3
N.A.
33.3
26.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
15
22
15
8
15
22
0
0
0
8
0
0
% D
% Glu:
0
8
0
0
0
29
8
0
8
0
15
8
15
8
8
% E
% Phe:
0
15
8
0
8
8
0
0
0
29
0
0
8
0
0
% F
% Gly:
8
29
15
0
0
0
0
0
8
8
0
36
0
0
15
% G
% His:
8
0
0
0
0
8
15
0
0
0
8
0
0
0
8
% H
% Ile:
8
8
8
8
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
22
22
0
0
0
0
0
0
0
8
0
8
0
% K
% Leu:
22
0
0
8
0
0
8
0
0
8
0
0
8
15
29
% L
% Met:
8
0
8
0
0
0
8
0
8
0
8
0
0
0
0
% M
% Asn:
0
8
8
0
36
8
0
0
8
8
0
0
22
0
0
% N
% Pro:
8
0
0
0
0
0
0
15
0
0
36
0
8
8
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
29
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
22
22
15
8
8
15
29
43
8
29
0
36
15
0
8
% S
% Thr:
0
0
0
0
8
8
8
8
0
8
8
0
8
8
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
8
0
0
29
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
22
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _